There is exciting chemical and physiological work to be done in Europe with the effects of New World poisons once we are sure that different poisons from different areas are properly distinguished. As far as our botanical knowledge about these poisonous plants is concerned we could sort out the differences only very slowly. Most Indians who make poison arrows completely ignore the nature of poisonous substances used by other tribes. A mystery surrounds the history of toxics and antidotes. Among wild Indians the preparation is the monopoly of piaches, who are priests, tricksters and doctors all at once; it is only with Indians from the missions that you can learn anything certain about such problematic matters. Centuries passed before any Europeans learned, thanks to Mutis's researches, that the bejuco del guaco is the most powerful antidote to snake bites, and which we were the first to describe botanically.